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3fj6

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Image:3fj6.jpg

Template:STRUCTURE 3fj6

Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2

Template:ABSTRACT PUBMED 19351152

About this Structure

3FJ6 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Davies M, Heikkila T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93. PMID:19351152 doi:10.1021/jm800963t

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