2k27

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Image:2k27.png

Template:STRUCTURE 2k27

Contents

Solution structure of Human Pax8 Paired Box Domain

Template:ABSTRACT PUBMED 18829450

Disease

Known disease associated with this structure: Hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia OMIM:[167415]

About this Structure

2K27 is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Codutti L, van Ingen H, Vascotto C, Fogolari F, Corazza A, Tell G, Quadrifoglio F, Viglino P, Boelens R, Esposito G. The solution structure of DNA-free Pax-8 paired box domain accounts for redox regulation of transcriptional activity in the pax protein family. J Biol Chem. 2008 Nov 28;283(48):33321-8. Epub 2008 Sep 30. PMID:18829450 doi:10.1074/jbc.M805717200

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