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1e50

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Revision as of 19:05, 10 June 2009 by OCA (Talk | contribs)
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Image:1e50.png

Template:STRUCTURE 1e50

Contents

AML1/CBF COMPLEX

Template:ABSTRACT PUBMED 10856244

Disease

Known disease associated with this structure: Leukemia, acute myeloid OMIM:[151385], Platelet disorder, familial, with associated myeloid malignancy OMIM:[151385], Rheumatoid arthritis, susceptibility to OMIM:[151385], Myeloid leukemia, acute, M4Eo subtype OMIM:[121360]

About this Structure

1E50 is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Warren AJ, Bravo J, Williams RL, Rabbitts TH. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta. EMBO J. 2000 Jun 15;19(12):3004-15. PMID:10856244 doi:10.1093/emboj/19.12.3004

Page seeded by OCA on Wed Jun 10 22:09:15 2009

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