3fxi

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Image:3fxi.png

Template:STRUCTURE 3fxi

Contents

Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex

Template:ABSTRACT PUBMED 19252480

Disease

Known disease associated with this structure: Endotoxin hyporesponsiveness OMIM:[603030], Colorectal cancer, susceptibility to OMIM:[603030], Longevity, susceptibility to OMIM:[603030], Macular degeneration, age-related, 10 OMIM:[603030]

About this Structure

3FXI is a 4 chains structure of sequences from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30;458(7242):1191-5. Epub 2009 Mar 1. PMID:19252480 doi:10.1038/nature07830

Page seeded by OCA on Wed Jun 10 22:12:40 2009

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