3ewj

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Image:3ewj.png

Template:STRUCTURE 3ewj

Crystal structure of catalytic domain of TACE with carboxylate inhibitor

Template:ABSTRACT PUBMED 19054672

About this Structure

3EWJ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Guo Z, Orth P, Wong SC, Lavey BJ, Shih NY, Niu X, Lundell DJ, Madison V, Kozlowski JA. Discovery of novel spirocyclopropyl hydroxamate and carboxylate compounds as TACE inhibitors. Bioorg Med Chem Lett. 2009 Jan 1;19(1):54-7. Epub 2008 Nov 14. PMID:19054672 doi:10.1016/j.bmcl.2008.11.034

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