2z5v

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Image:2z5v.png

Template:STRUCTURE 2z5v

Contents

Solution structure of the TIR domain of human MyD88

Template:ABSTRACT PUBMED 19506249

Disease

Known disease associated with this structure: Pyogenic bacterial infections, recurrent, due to MYD88 deficiency OMIM:[602170]

About this Structure

2Z5V is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Ohnishi H, Tochio H, Kato Z, Orii KE, Li A, Kimura T, Hiroaki H, Kondo N, Shirakawa M. Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10260-5. Epub 2009 Jun 8. PMID:19506249

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