3h0b

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Image:3h0b.jpg

Template:STRUCTURE 3h0b

Discovery of aminoheterocycles as a novel beta-secretase inhibitor class

Template:ABSTRACT PUBMED 19409780

About this Structure

3H0B is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Stachel SJ, Coburn CA, Rush D, Jones KL, Zhu H, Rajapakse H, Graham SL, Simon A, Katharine Holloway M, Allison TJ, Munshi SK, Espeseth AS, Zuck P, Colussi D, Wolfe A, Pietrak BL, Lai MT, Vacca JP. Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2977-80. Epub 2009 Apr 18. PMID:19409780 doi:10.1016/j.bmcl.2009.04.033

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