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C-di-GMP
From Proteopedia
Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)
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C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.
is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.
Several protein structures involved in c-di-GMP signaling have been determined (reviewed in User:Tilman_Schirmer/Sandbox_200).
References
Reviews:
- Hengge R. Principles of c-di-GMP signalling in bacteria. Nat Rev Microbiol. 2009 Apr;7(4):263-73. PMID:19287449 doi:10.1038/nrmicro2109
- Jenal U, Malone J. Mechanisms of cyclic-di-GMP signaling in bacteria. Annu Rev Genet. 2006;40:385-407. PMID:16895465 doi:10.1146/annurev.genet.40.110405.090423
