2v43
From Proteopedia
|
CRYSTAL STRUCTURE OF RSEB: A SENSOR FOR PERIPLASMIC STRESS RESPONSE IN E. COLI
Overview
An elegant network of signal transduction has evolved in the bacterial, cell envelope to respond to environmental stress. It is initiated by, sensing unfavourable and harmful changes in the periplasm. The stress, signal is then transmitted by a controlled degradation of the, transmembrane anti-sigma-factor RseA that leads to the activation of the, alternative sigma factor sigma(E). The periplasmic protein RseB exerts a, crucial role in modulating the stability of RseA. RseB from Escherichia, coli has been crystallized and crystal structures were determined at 2.4 A, and at 2.8 A resolution. The protein forms a homodimer, with the monomer, composed of two domains. The large domain resembles an unclosed, beta-barrel that is structurally remarkably similar to a protein family, capable of ... [(full description)]
About this Structure
2V43 is a [Single protein] structure of sequence from [Escherichia coli] with CYS as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
The Structure of RseB: A Sensor in Periplasmic Stress Response of E. coli., Wollmann P, Zeth K, J Mol Biol. 2007 Jun 19;. PMID:17692869
Page seeded by OCA on Tue Oct 30 08:29:57 2007
