3f3w
From Proteopedia
Drug resistant cSrc kinase domain in complex with inhibitor RL45 (Type II)
Template:ABSTRACT PUBMED 19462975
About this Structure
3F3W is a 2 chains structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.
Reference
- Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928
Page seeded by OCA on Wed Jul 22 20:56:16 2009
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Getlik, M. | Grutter, C. | Kluter, S. | Rauh, D. | Allosteric | Alternative splicing | Atp-binding | Dfg-out | Drug resistance mutation | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Sh2 domain | Sh3 domain | Transferase | Type ii | Tyrosine-protein kinase
