3ii6

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Image:3ii6.jpg

Template:STRUCTURE 3ii6

Contents

Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.

Disease

Known disease associated with this structure: LIG4 syndrome OMIM:[601837], Multiple myeloma, resistance to OMIM:[601837]

About this Structure

3II6 is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wu PY, Frit P, Meesala S, Dauvillier S, Modesti M, Andres SN, Huang Y, Sekiguchi J, Calsou P, Salles B, Junop MS. Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4. Mol Cell Biol. 2009 Jun;29(11):3163-72. Epub 2009 Mar 30. PMID:19332554 doi:10.1128/MCB.01895-08

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