3eek

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Image:3eek.jpg

Template:STRUCTURE 3eek

Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-(4-methylphenyl)phenyl)prop-1-ynyl]-6-methylpyrimidine(UCP111D4M) and NADPH

Template:ABSTRACT PUBMED 19152636

About this Structure

3EEK is a 2 chains structure of sequences from Candida glabrata. Full crystallographic information is available from OCA.

Reference

  • Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors. Chem Biol Drug Des. 2009 Jan;73(1):62-74. PMID:19152636 doi:10.1111/j.1747-0285.2008.00745.x

Page seeded by OCA on Wed Aug 19 13:12:51 2009

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