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1g2b

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Image:1g2b.jpg

1g2b, resolution 1.12Å

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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48

Overview

The crystal structure of an alpha-spectrin Src-homology 3 (SH3) domain, mutant has been refined at 1.12 A resolution. This X-ray structure is at, the highest resolution achieved so far for an SH3 domain. The structure, allows the identification of a complete set of specific interactions and, is useful for the elucidation of relations between structure and, pH-dependent thermodynamic stability in a series of SH3 domain mutants.

About this Structure

1G2B is a Single protein structure of sequence from Gallus gallus with SO4 as ligand. Full crystallographic information is available from OCA.

Reference

Atomic resolution structure of a mutant of the spectrin SH3 domain., Berisio R, Viguera A, Serrano L, Wilmanns M, Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):337-40. PMID:11173498

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