3igg

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Image:3igg.jpg

Template:STRUCTURE 3igg

Novel CDK-5 inhibitors - crystal structure of inhibitor EFQ with CDK-2

Template:ABSTRACT PUBMED 19700321

About this Structure

3IGG is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Helal CJ, Kang Z, Lucas JC, Gant T, Ahlijanian MK, Schachter JB, Richter KE, Cook JM, Menniti FS, Kelly K, Mente S, Pandit J, Hosea N. Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer's disease. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5703-7. Epub 2009 Aug 8. PMID:19700321 doi:10.1016/j.bmcl.2009.08.019

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