3g86
From Proteopedia
Hepatitis C virus polymerase NS5B (BK 1-570) with thiazine inhibitor
Template:ABSTRACT PUBMED 19457662
About this Structure
3G86 is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Adjabeng G, Elworthy TR, Tracy J, Chin E, Li J, Wang B, Bamberg JT, Stephenson R, Oshiro C, Harris SF, Ghate M, Leveque V, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Larrabee S, Brandl M, Briggs A, Sukhtankar S, Farrell R, Xu B. Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3642-6. Epub 2009 May 7. PMID:19457662 doi:10.1016/j.bmcl.2009.05.004
Page seeded by OCA on Wed Sep 9 09:31:28 2009
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Ghate, M. | Harris, S F. | Acetylation | Apoptosis | Atp-binding | Capsid protein | Cell membrane | Cytoplasm | Endoplasmic reticulum | Envelope protein | Fusion protein | Glycoprotein | Hcv | Helicase | Hepatitis | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Ns5b | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Protease | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Thiol protease | Transcription | Transcription regulation | Transferase | Transferase rna-dependent rna polymerase | Transmembrane | Ubl conjugation | Viral nucleoprotein | Virion | Zinc
