3hrb

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Image:3hrb.png

Template:STRUCTURE 3hrb

p38 kinase Crystal structure in complex with small molecule inhibitor

Template:ABSTRACT PUBMED 19678708

About this Structure

3HRB is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lumeras W, Caturla F, Vidal L, Esteve C, Balague C, Orellana A, Dominguez M, Roca R, Huerta JM, Godessart N, Vidal B. Design, Synthesis, and Structure-Activity Relationships of Aminopyridine N-Oxides, a Novel Scaffold for the Potent and Selective Inhibition of p38 Mitogen Activated Protein Kinase. J Med Chem. 2009 Aug 14. PMID:19678708 doi:10.1021/jm9008604

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