3gpw
From Proteopedia
Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand
Template:ABSTRACT PUBMED 19678642
About this Structure
3GPW is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x
Page seeded by OCA on Wed Sep 16 09:02:11 2009
Categories: Proteasome endopeptidase complex | Saccharomyces cerevisiae | Arthur, K A.M. | Groll, M. | Macherla, V R. | Manam, R R. | Potts, C B. | Cancer therapy | Cytoplasm | Hydrolase | Immunology | Isopeptide bond | Nucleus | Phosphoprotein | Protease | Proteasome | Threonine protease | Time-dependent elimination of a defined leaving group | Ubiquitin | Ubl conjugation | Zymogen
