3i0r

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Image:3i0r.png

Template:STRUCTURE 3i0r

crystal structure of HIV reverse transcriptase in complex with inhibitor 3

Template:ABSTRACT PUBMED 19631528

About this Structure

3I0R is a 2 chains structure of sequences from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

Reference

  • Su DS, Lim JJ, Tinney E, Wan BL, Young MB, Anderson KD, Rudd D, Munshi V, Bahnck C, Felock PJ, Lu M, Lai MT, Touch S, Moyer G, Distefano DJ, Flynn JA, Liang Y, Sanchez R, Prasad S, Yan Y, Perlow-Poehnelt R, Torrent M, Miller M, Vacca JP, Williams TM, Anthony NJ. Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5119-23. Epub 2009 Jul 10. PMID:19631528 doi:10.1016/j.bmcl.2009.07.031

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