3f66
From Proteopedia
Contents |
Human c-Met Kinase in complex with quinoxaline inhibitor
Template:ABSTRACT PUBMED 19059779
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
3F66 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M. Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):397-400. Epub 2008 Nov 21. PMID:19059779 doi:10.1016/j.bmcl.2008.11.062
Page seeded by OCA on Mon Sep 21 20:14:22 2009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Ceska, T. | Meier, C. | Alternative splicing | Atp-binding | C-met | Chromosomal rearrangement | Disease mutation | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Protein kinase | Proto-oncogene | Quinoxaline | Receptor | Repeat | Signal | Transferase | Transmembrane | Tyrosine-protein kinase.
