3hus

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Template:STRUCTURE 3hus

Contents 1 Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide 2 Disease 3 About this Structure 4 Reference

Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide

Template:ABSTRACT PUBMED 19650644

Disease

Known disease associated with this structure: Afibrinogenemia, congenital OMIM:[134820], Amyloidosis, hereditary renal OMIM:[134820], Dysfibrinogenemia, alpha type, causing bleeding diathesis OMIM:[134820], Dysfibrinogenemia, alpha type, causing recurrent thrombosis OMIM:[134820], Afibrinogenemia, congenital OMIM:[134830], Dysfibrinogenemia, beta type OMIM:[134830], Thrombophilia, dysfibrinogenemic OMIM:[134830]

About this Structure

3HUS is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Bowley SR, Okumura N, Lord ST. Impaired protofibril formation in fibrinogen N308K is due to altered D:D and A:a interactions. Biochemistry. 2009 Aug 3. PMID:19650644 doi:10.1021/bi900239b

Page seeded by OCA on Wed Sep 23 08:22:54 2009