2y4e

Structural highlights

Function

EFEB_ECOLI Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. Also displays peroxidase activity on guaiacol in vitro.^{[1] [2]}

References

1. ↑ Sturm A, Schierhorn A, Lindenstrauss U, Lilie H, Brüser T. YcdB from Escherichia coli reveals a novel class of Tat-dependently translocated hemoproteins. J Biol Chem. 2006 May 19;281(20):13972-8. PMID:16551627 doi:10.1074/jbc.M511891200
2. ↑ Letoffe S, Heuck G, Delepelaire P, Lange N, Wandersman C. Bacteria capture iron from heme by keeping tetrapyrrol skeleton intact. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11719-24. doi:, 10.1073/pnas.0903842106. Epub 2009 Jun 29. PMID:19564607 doi:http://dx.doi.org/10.1073/pnas.0903842106