5d9x

Structural highlights

Function

DHAR1_ORYSJ Involved in ascorbate homeostasis. Maintains redox pools of ascorbate by recycling dihydroascorbate (DHA) to ascorbate (Probable). Involved in scavenging reactive oxygen species (ROS) under oxidative stresses. Possesses dehydroascorbate reductase (DHAR) activity in vitro (PubMed:19011360). May function via a ping-pong reaction mechanism with an electron transfer at the active site (PubMed:26775680). Possesses chaperone-like activity in vitro (PubMed:26775680).^{[1] [2] [3]}

References

1. ↑ Shin SY, Kim IS, Kim YH, Park HM, Lee JY, Kang HG, Yoon HS. Scavenging reactive oxygen species by rice dehydroascorbate reductase alleviates oxidative stresses in Escherichia coli. Mol Cells. 2008 Dec 31;26(6):616-20 PMID:19011360
2. ↑ Do H, Kim IS, Jeon BW, Lee CW, Park AK, Wi AR, Shin SC, Park H, Kim YS, Yoon HS, Kim HW, Lee JH. Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica. Sci Rep. 2016 Jan 18;6:19498. doi: 10.1038/srep19498. PMID:26775680 doi:http://dx.doi.org/10.1038/srep19498
3. ↑ Kim YS, Kim IS, Bae MJ, Choe YH, Kim YH, Park HM, Kang HG, Yoon HS. Homologous expression of cytosolic dehydroascorbate reductase increases grain yield and biomass under paddy field conditions in transgenic rice (Oryza sativa L. japonica). Planta. 2013 Jun;237(6):1613-25. PMID:23519921 doi:10.1007/s00425-013-1862-8