5dvw

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Structure of minor nucleoprotein V30 from Zaire ebolavirus

Structural highlights

5dvw is a 4 chain structure with sequence from Ebola virus - Mayinga, Zaire, 1976. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.75Å
Ligands:EDO
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

VP30_EBOZM Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA stem-loop at the transcription start site of the first gene. Binds to RNA.[1]

See Also

References

  1. ↑ Weik M, Modrof J, Klenk HD, Becker S, Muhlberger E. Ebola virus VP30-mediated transcription is regulated by RNA secondary structure formation. J Virol. 2002 Sep;76(17):8532-9. PMID:12163572

Contents


PDB ID 5dvw

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OCA

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