5jgz

From Proteopedia

Spin-Labeled T4 Lysozyme Construct T151V1

Structural highlights

5jgz is a 1 chain structure with sequence from Escherichia phage T4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.534Å
Ligands:	CL, HEZ, K, PO4, V1A
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ENLYS_BPT4 Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.^[1]

References

↑ Moussa SH, Kuznetsov V, Tran TA, Sacchettini JC, Young R. Protein determinants of phage T4 lysis inhibition. Protein Sci. 2012 Apr;21(4):571-82. doi: 10.1002/pro.2042. Epub 2012 Mar 2. PMID:22389108 doi:http://dx.doi.org/10.1002/pro.2042

1 Structural highlights
2 Function
3 See Also
4 References

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PDB ID 5jgz

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Categories: Escherichia phage T4 | Large Structures | Balo AR | Ernst OP | Feyrer H

5jgz

From Proteopedia

Spin-Labeled T4 Lysozyme Construct T151V1

Structural highlights

Function

See Also

References

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