6rlp
From Proteopedia
Cryo-EM reconstruction of TMV coat protein
Structural highlights
FunctionCAPSD_TMV Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA. Publication Abstract from PubMedRecent improvements in direct electron detectors, microscope technology and software provided the stimulus for a ;quantum leap' in the application of cryo-electron microscopy in structural biology, and many national and international centres have since been created in order to exploit this. Here, a new facility for cryo-electron microscopy focused on single-particle reconstruction of biological macromolecules that has been commissioned at the European Synchrotron Radiation Facility (ESRF) is presented. The facility is operated by a consortium of institutes co-located on the European Photon and Neutron Campus and is managed in a similar fashion to a synchrotron X-ray beamline. It has been open to the ESRF structural biology user community since November 2017 and will remain open during the 2019 ESRF-EBS shutdown. CM01: a facility for cryo-electron microscopy at the European Synchrotron.,Kandiah E, Giraud T, de Maria Antolinos A, Dobias F, Effantin G, Flot D, Hons M, Schoehn G, Susini J, Svensson O, Leonard GA, Mueller-Dieckmann C Acta Crystallogr D Struct Biol. 2019 Jun 1;75(Pt 6):528-535. doi: , 10.1107/S2059798319006880. Epub 2019 May 28. PMID:31205015[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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