Structural highlights
Function
PEPT_YERP4 Mediates the proton-dependent uptake of dipeptides. Shows higher affinity for dipeptides with a negatively charged amino acid residue at the N-terminal position, such as Asp-Ala and Glu-Ala. Also displays specificity for Ala-Ala, Ala-Tyr and Tyr-Ala.[1]
References
- ↑ Boggavarapu R, Jeckelmann JM, Harder D, Ucurum Z, Fotiadis D. Role of electrostatic interactions for ligand recognition and specificity of peptide transporters. BMC Biol. 2015 Aug 6;13(1):58. doi: 10.1186/s12915-015-0167-8. PMID:26246134 doi:http://dx.doi.org/10.1186/s12915-015-0167-8