Structural highlights
Function
MNMM_STAA8 Involved in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA (PubMed:36762482). Catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34 to form mnm(5)s(2)U34 (PubMed:36762482).[1]
References
- ↑ Cho G, Lee J, Kim J. Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res. 2023 Feb 28;51(4):1971-1983. PMID:36762482 doi:10.1093/nar/gkad048
