8kel

Structural highlights

Function

EXOD_BPT4 3'-5' exonuclease that preferentially uses ssDNA as substrate. Plays a role in group I intron homing. May play a role in the final step of host DNA degradation, by scavenging DNA into mononucleotides.^{[1] [2]}

References

1. ↑ Huang YJ, Parker MM, Belfort M. Role of exonucleolytic degradation in group I intron homing in phage T4. Genetics. 1999 Dec;153(4):1501-12. PMID:10581261 doi:10.1093/genetics/153.4.1501
2. ↑ Gruber H, Kern G, Gauss P, Gold L. Effect of DNA sequence and structure on nuclease activity of the DexA protein of bacteriophage T4. J Bacteriol. 1988 Dec;170(12):5830-6. PMID:3056918 doi:10.1128/jb.170.12.5830-5836.1988