8ofy

Structural highlights

Function

AQP2_TRYBB Mediates water and glycerol transport across cell membranes (PubMed:15294911, PubMed:21471730). Permeable to urea (PubMed:15294911). Permeable to methylamine/methylammonium (PubMed:16889642). Permeable to dihydroxyacetone (PubMed:15294911).^{[1] [2] [3]}

References

1. ↑ Uzcategui NL, Szallies A, Pavlovic-Djuranovic S, Palmada M, Figarella K, Boehmer C, Lang F, Beitz E, Duszenko M. Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei. J Biol Chem. 2004 Oct 8;279(41):42669-76. PMID:15294911 doi:10.1074/jbc.M404518200
2. ↑ Zeuthen T, Wu B, Pavlovic-Djuranovic S, Holm LM, Uzcategui NL, Duszenko M, Kun JF, Schultz JE, Beitz E. Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypansoma brucei. Mol Microbiol. 2006 Sep;61(6):1598-608. PMID:16889642 doi:10.1111/j.1365-2958.2006.05325.x
3. ↑ Bassarak B, Uzcátegui NL, Schönfeld C, Duszenko M. Functional characterization of three aquaglyceroporins from Trypanosoma brucei in osmoregulation and glycerol transport. Cell Physiol Biochem. 2011;27(3-4):411-20. PMID:21471730 doi:10.1159/000327968