Structural highlights
Function
CNGC1_ARATH Acts as a cyclic nucleotide-gated ion channel. Can be activated by cyclic AMP which leads to an opening of the cation channel. May be responsible for cAMP-induced calcium entry in cells and thus should be involved in the calcium signal transduction. Could transport K(+), Na(+) and Pb(2+).[1] [2]
References
- ↑ Sunkar R, Kaplan B, Bouché N, Arazi T, Dolev D, Talke IN, Maathuis FJ, Sanders D, Bouchez D, Fromm H. Expression of a truncated tobacco NtCBP4 channel in transgenic plants and disruption of the homologous Arabidopsis CNGC1 gene confer Pb2+ tolerance. Plant J. 2000 Nov;24(4):533-42. PMID:11115134 doi:10.1046/j.1365-313x.2000.00901.x
- ↑ Leng Q, Mercier RW, Hua BG, Fromm H, Berkowitz GA. Electrophysiological analysis of cloned cyclic nucleotide-gated ion channels. Plant Physiol. 2002 Feb;128(2):400-10. PMID:11842144 doi:10.1104/pp.010832