Structural highlights
Function
TOPS_BPT4 Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. T4 topoisomerase makes double-strand breaks.TOPL_BPT4 Large subunit of the DNA topoisomerase that untwists superhelical DNA. Controls of topological states of double-stranded DNA by transient breakage and subsequent rejoining of DNA strands.[1]
References
- ↑ Stetler GL, King GJ, Huang WM. T4 DNA-delay proteins, required for specific DNA replication, form a complex that has ATP-dependent DNA topoisomerase activity. Proc Natl Acad Sci U S A. 1979 Aug;76(8):3737-41. PMID:226976 doi:10.1073/pnas.76.8.3737
