9njr

Structural highlights

Function

DMC1_YEAST Required for meiotic recombination, synaptonemal complex formation and cell cycle progression. Recruited to meiosis recombination hotspots by MEI5 and SAE3.^{[1] [2]}

References

1. ↑ Hayase A, Takagi M, Miyazaki T, Oshiumi H, Shinohara M, Shinohara A. A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1. Cell. 2004 Dec 29;119(7):927-40. PMID:15620352 doi:10.1016/j.cell.2004.10.031
2. ↑ Dresser ME, Ewing DJ, Conrad MN, Dominguez AM, Barstead R, Jiang H, Kodadek T. DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway. Genetics. 1997 Oct;147(2):533-44. PMID:9335591 doi:10.1093/genetics/147.2.533