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Arnold lab: coenzyme specificity

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The Arnold lab wanted to establish a generalized procedure to change the cofactor specificity of certain enzymes from NADPH to NADH. [1]

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References

  1. ↑ Brinkmann-Chen S, Flock T, Cahn JK, Snow CD, Brustad EM, McIntosh JA, Meinhold P, Zhang L, Arnold FH. General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10946-51. doi:, 10.1073/pnas.1306073110. Epub 2013 Jun 17. PMID:23776225 doi:10.1073/pnas.1306073110

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Karsten Theis

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