Focal adhesion kinase 3D structures

From Proteopedia

3D Structures of focal adhesion kinase

Updated on 06-March-2023

Focal adhesion kinase 1 (FAK1)

FAK1 targeting domain 891-1052

1k04, 1k05, 3s9o, 2l6h, 2l6g, 2l6f – hFAK1 – human

1ow6, 1ow7 - hFAK1 + paxillin LD4 motif

1ow8 - hFAK1 + paxillin LD2 motif

3b71 - hFAK1 + ADP + ATP

1k40 – mFAK1 – mouse

5f28 – mFAK1 + MEF2C

1ktm, 1qvx, 1pv3 - cFAK1 – chicken – NMR

FAK1 kinase domain 411-686

1mp8 - hFAK1

2etm, 3bz3, 4gu9, 4kab, 4k9y, 4i4e, 4i4f, 4k8a, 4gu6, 4brx, 4ebv, 4ebw, 3pxk, 4q9s, 6i8z - hFAK1 + inhibitor

4kao - hFAK1 (mutant) + pyrazole derivative

2ijm - hFAK1 + ADP + ATP

4d4r, 4d4s, 4d4v, 4d4y, 4d55, 4d5h, 4d5k - cFAK1

2j0l - cFAK1 phosphorylated

2jkk, 2jkm, 2jko, 2jkq, 4d58, 6yoj, 6yq1, 6yr9, 6yt6, 6yvs, 6yvy, 6yxv - cFAK1 + pyrimidine derivative

4c7t, 6gcr, 6gcw, 6gcx - cFAK1 + inhibitor

FAK1 FERM domain 31-405

4cye - hFAK1

4ny0 - hFAK1 (mutant)

2j0j, 2j0k, 2j0m - cFAK1 kinase + FERM domains

2aeh, 2al6, 6cb0 - cFAK1

3zdt - cFAK1 (mutant)

FAK1 FAT domain 749-874

7w7z, 7w8i, 7w9u - hFAK1

6pw8 – hFAK1 + paxillin peptide

6bz3 – mFAK1 + netrin receptor peptide

FAK1 FERM+kinase domains 30-696

6ty4 - hFAK1 + AMPPNP – Cryo EM

6ty3 - cFAK1

Focal adhesion kinase 2 (FAK2) See Pyk2 in Tyrosine kinase