Tryptophan synthase 3D structures

From Proteopedia

3D structures of tryptophan synthase

Updated on 29-January-2024 - For a general description of the protein see Tryptophan synthase

Tryptophan synthase α subunit

1rd5 - TrpS α subunit – corn

3vnd - TrpS α subunit – Shewanella frigidimarina

3tha - TrpS α subunit – Campylobacter jejuni

3nav - TrpS α subunit – Vibrio cholerae

1geq - PfTrpS α subunit - Pyrococcus furiosus

2dzp, 2dzs, 2dzt, 2dzu, 2dzv, 2dzw, 2dzx, 2e09 - PfTrpS α subunit (mutant)

1ujp - TtTrpS α subunit

1v7y, 1wq5, 1xc4 - EcTrpS α subunit

1xcf - EcTrpS α subunit (mutant)

2ekc - TrpS α subunit – Aquifex aeolicus

5kmy, 5k9x, 6oky - TrpS α subunit – Legionella pneumophila

5n2p - SsTrpS α subunit – Sulfolobus solfataricus

6oso, 6ouy - StTrpS α subunit – Salmonella typhimurium

6qky - SpTrpS α subunit – Streptococcus pneumoniae

Tryptophan synthase α binary complex

1wxj - TtTrpS α subunit + indole propanol phosphate

Tryptophan synthase β subunit

1x1q - TtTrpS β subunit – Thermus thermophilus

2dh6 - EcTrpS β subunit - Escherichia coli

2o2e, 2o2j - MtTrpS β subunit – Mycobacterium tuberculosis

1v8z, 5vm5, 6am7, 6am9, 6amc, 6amh, 6cuv - PfTrpS β1 subunit

4neg - TrpS β subunit – Bacillus anthracis

Tryptophan synthase β complex

2dh5 - EcTrpS β subunit + PLP

4qys, 6hte - SsTrpS β2 subunit + PLP

5dvz - PfTrpS β1 subunit + PLP derivative

6am7, 6amc, 6cuv, 7rnq - PfTrpS β1 subunit (mutant) + PLP derivative

5dw0 - PfTrpS β1 subunit + Ser derivative

5dw3 - PfTrpS β1 subunit + PLP derivative + Trp

6am8, 6ami - PfTrpS β1 subunit (mutant) + PLP derivative + Trp

5t6m - PfTrpS β1 subunit + PLP derivative + Trp derivative

7rnp, 7rof - PfTrpS β1 subunit (mutant) + PLP derivative + Trp derivative

6xsy - PfTrpS β1 subunit (mutant) + PLP derivative + inhibitor

5vm5 - PfTrpS β1 subunit + PLP derivative + Ser derivative

5ixj - PfTrpS β1 subunit + PLP derivative + Thr

6am9, 6amh - PfTrpS β1 subunit (mutant) + PLP-Ser derivative

6cut - PfTrpS β1 subunit (mutant) + Trp analog

6cuz - PfTrpS β1 subunit (mutant) + PLP derivative + ethylserine

8egy, 8egz - TmTrpS β1 subunit + PLP derivative – Thermotoga maritima

8eh0 - TmTrpS β1 subunit + PLP derivative + quinoline derivative

Tryptophan synthase α+β subunits

1wdw - PfTrpS α + β subunits

5tcf - MtTrpS α + β

6wdu, 7a20, 7l5h, 7lev - StTrpS α + β

7kq9 - StTrpS α + β (mutant)

6v82 - TrpS α + β – Chlamydia trachomatis

Tryptophan synthase α+β binary complex

1ttp, 1ttq, 1bks, 2wsy, 1kfk, 7l4d, 7lx1, 8b03 - StTrpS α + β + PLP

6dz4, 8b05, 8b08 - StTrpS α + β + PLP derivative

1k7x, 2j9z, 7kmc, 7l47 - StTrpS α + β (mutant) + PLP

3pr2, 4hn4, 4hpj, 4hpx, 4ht3, 4kkx, 7kwv, 7kxc, 7kyt, 7l03 - StTrpS α + β + inhibitor

1kfj - StTrpS α + β + pyridoxal-serine-monophsphate

1a5a, 1k8x - StTrpS α (mutant) + β + PLP

1kfe - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate

7ku9, 7l1h, 7lgx, 7mt4, 7mt5, 7mt6 - StTrpS α + β + inhibitor

6o1h, 6dzo, 6duc, 6d0v, 6c73, 6x0c, 7jmq, 7kbn, 7ki7 - StTrpS α + β (mutant) + inhibitor

2j9y, 7lt4 - StTrpS α + β (mutant) + enoic acid derivative

6xrh, 6xt0 - StTrpS α + β (mutant) + IGP + Ala derivative

7jqw, 7k5a - StTrpS α + β (mutant) + Ser

2tys - StTrpS α (mutant) + β (mutant) + Trp derivative

5kzm - TrpS α + β + PLP derivative – Francisella tularensis

5kin - SpTrpS α + β + PLP derivative – Streptococcus pneumoniae

5e0k - PfTrpS α + β + PLP derivative

5ocw, 5tcg, 5tci, 5tcj - MtTrpS α + β + inhibitor

5tcf - MtTrpS α + β + PLP derivative

5tch - MtTrpS α + β (mutant) + PLP derivative

5e0k - PfTrpS α + β + PLP derivative

5ey5 - TrpS α + β + PLP - synthetic

Tryptophan synthase α+β ternary complex with PLP and inhibitor

1a50, 1cw2, 1c9d, 1cx9, 1c8v, 1c29, 2cle, 2clh, 2cli, 2clk, 2cll, 2clm, 2clo, 2clf, 5bw6, 4zqc, 4y6g, 4xug, 4wx2, 5bw6, 6vnt, 6wx3, 6xin, 7kqf, 7lpf, 7lvx, 7ly8, 7m2l, 7m3s, 7me8 - StTrpS α + β + inhibitor + PLP

1fuy, 7jhw, 7kh6 - StTrpS α + β (mutant) + inhibitor + PLP

6xe3 - StTrpS α + β (mutant) + inhibitor + PLP derivative

Tryptophan synthase α+β ternary complex with PLP and IGP derivatives

1a5b, 1kfb - StTrpS α (mutant) + β + IGP + PLP

1k8z - StTrpS α + β (mutant) + IGP derivative + PLP

1kfc - StTrpS α (mutant) + β + IGP derivative + PLP

1k3u, 1k7e, 1k7f - StTrpS α + β + IGP derivative + PLP

1qoq, 2rh9, 2rhg - StTrpS α + β + IGP + PLP

1qop - StTrpS α + β + IGP analog + PLP

2trs, 1beu - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + IGP analog

Tryptophan synthase α+β ternary complex with PLP and G3P derivatives

1wbj - StTrpS α + β + G3P + PLP

2j9x - StTrpS α + β + G3P + acrylic acid derivative

1k8y - StTrpS α + β (mutant) + G3P derivative + PLP

1tjp - StTrpS α + β + G3P derivative + PLP

2tsy - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + G3P

Other TrpS α+β ternary complex

6hul - SsTrpS α + β subunits + PLP + Ser

8b06 - StTrpS α + β + Ser + PLP

7k0b - StTrpS α + β (mutant) + Ser + PLP

1ubs - StTrpS α (mutant) + β (mutant) + Ser + PLP

7jtt, 7ka1 - StTrpS α + β (mutant) + Ser + inhibitor

6vfd - StTrpS α + β + quinoid derivative + Ser

6xnc, 6xoy - StTrpS α + β + IGP + Trp derivative

7lut - StTrpS α + β + PLP + Trp

6usa - MtTrpS α + β + PLP derivative + piperazine derivative

Tryptophan synthase α+β quaternary complex

1a5s - StTrpS α + β + Ser + inhibitor + PLP

5cgq, 7lkl, 7ltp - StTrpS α + β + Trp + inhibitor + PLP

7lv5 - StTrpS α + β + His + inhibitor + PLP

7jll - StTrpS α + β (mutant) + Trp + inhibitor + PLP

3cep - StTrpS α + β + G3P + indoline + PLP

6uap, 6ub9, 6dwe, 6e9p - MtTrpS α + β + malonate + inhibitor + PLP derivative

6u6c - MtTrpS α + β + PLP derivative + sulfonamide derivative + Ala

Dimethylallyl tryptophan synthase or tryptophan 6-prenyltransferase

3i4z - AfDATrpS – Aspergillus fumigatus

3i4x - AfDATrpS + DMAPP + Trp

4ld7 - DATrpS + thiopyrophosphate – Neosartoria fischeri<br />

6zs0 - ScDATrpS – Stretptomyces coelicolor

5inj, 6zrz, 7w8v, 7w8w, 7w8x - ScDATrpS + DMASPP + Trp

7y8y - ScDATrpS + thiopyrophosphate + DMASPP + Trp

6zry - MoDATrpS + Trp – Micromonospora olivasterospora

6zrx - MoDATrpS + DMAPP + Trp