Structural highlights
Function
MGT4A_HUMAN Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:17006639). Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity).[UniProtKB:Q812G0][1]
References
- ↑ Oguri S, Yoshida A, Minowa MT, Takeuchi M. Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes. Glycoconj J. 2006 Nov;23(7-8):473-80. PMID:17006639 doi:http://dx.doi.org/10.1007/s10719-006-6216-3
