Structural highlights
Function
A0A8S0GSD4_9CNID
Publication Abstract from PubMed
StayGold is an exceptionally bright and stable fluorescent protein that is highly resistant to photobleaching. Despite favorable fluorescence properties, use of StayGold as a fluorescent tag is limited because it forms a natural dimer. Here we report the 1.6 A structure of StayGold and generate a derivative, mStayGold, that retains the brightness and photostability of the original protein while being fully monomeric.
A monomeric StayGold fluorescent protein.,Ivorra-Molla E, Akhuli D, McAndrew MBL, Scott W, Kumar L, Palani S, Mishima M, Crow A, Balasubramanian MK Nat Biotechnol. 2024 Sep;42(9):1368-1371. doi: 10.1038/s41587-023-02018-w. Epub , 2023 Dec 11. PMID:38081970[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Ivorra-Molla E, Akhuli D, McAndrew MBL, Scott W, Kumar L, Palani S, Mishima M, Crow A, Balasubramanian MK. A monomeric StayGold fluorescent protein. Nat Biotechnol. 2024 Sep;42(9):1368-1371. PMID:38081970 doi:10.1038/s41587-023-02018-w
