9az4

Structural highlights

Disease

INF2_HUMAN Autosomal dominant intermediate Charcot-Marie-Tooth disease type E;Genetic steroid-resistant nephrotic syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.

Function

INF2_HUMAN Severs actin filaments and accelerates their polymerization and depolymerization.