Structural highlights
Function
BIN1_RAT May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Owen DJ, Wigge P, Vallis Y, Moore JD, Evans PR, McMahon HT. Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation. EMBO J. 1998 Sep 15;17(18):5273-85. PMID:9736607 doi:10.1093/emboj/17.18.5273
