1f7t

Structural highlights

Function

ACPS_BACSU Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP. Also modifies the D-alanyl carrier protein but fails to recognize PCP and AcpK, an acyl carrier protein of secondary metabolism.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• Acyl carrier protein synthase
• Acyl carrier protein synthase 3D structures
• Proteins from Mycobacterium tuberculosis

References

1. ↑ Mootz HD, Finking R, Marahiel MA. 4'-phosphopantetheine transfer in primary and secondary metabolism of Bacillus subtilis. J Biol Chem. 2001 Oct 5;276(40):37289-98. Epub 2001 Aug 6. PMID:11489886 doi:http://dx.doi.org/10.1074/jbc.M103556200