Structural highlights
Function
Q5L2U2_GEOKA
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The crystal structure of a conserved hypothetical protein, GK0453, from Geobacillus kaustophilus has been determined to 2.2 A resolution. The crystal belonged to space group P43212, with unit-cell parameters a = b = 75.69, c = 64.18 A. The structure was determined by the molecular-replacement method and was refined to a final R factor of 22.6% (Rfree = 26.3%). Based on structural homology, the GK0453 protein possesses two independent binding sites and hence it may simultaneously interact with two proteins or with a protein and a nucleic acid.
Structure of the hypothetical DUF1811-family protein GK0453 from Geobacillus kaustophilus HTA426.,Padmanabhan B, Nakamura Y, Antonyuk SV, Strange RW, Hasnain SS, Yokoyama S, Bessho Y Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):342-5. doi:, 10.1107/S1744309113003369. Epub 2013 Mar 28. PMID:23545635[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Padmanabhan B, Nakamura Y, Antonyuk SV, Strange RW, Hasnain SS, Yokoyama S, Bessho Y. Structure of the hypothetical DUF1811-family protein GK0453 from Geobacillus kaustophilus HTA426. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):342-5. doi:, 10.1107/S1744309113003369. Epub 2013 Mar 28. PMID:23545635 doi:http://dx.doi.org/10.1107/S1744309113003369
