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3D structures of mitogen-activated protein kinase kinase kinase kinase

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3D structures of mitogen-activated protein kinase kinase kinase kinase or hematopoietic progenitor kinase

Updated on 29-December-2025

Mitogen-activated protein kinase kinase kinase kinase; Domains – kinase 1-307; Citron homology 481-821;

6nfy, 6nfz – hHPK1 kinase domain + cancer drug - human
6ng0 – hHPK1 kinase domain (mutant) + cancer drug
6cqf, 7l24. 7l25, 7l26, 7m0k, 7m0m, 7r9l, 7r9n, 7r9p, 7r9t, 7siu, 8cdw, 8cij, 8par, 8pas, 9bi8, 9bik, 9bj1, 9n7r, 9n9x, 9nac, 9nbs, 9nc2 – hHPK1 kinase domain + inhibitor
6cqe, 7kac, 8fh4, 8fjz, 8fko, 8xn7, 9czt, 9czu, 9czx, 9d00, 9h8d, 9h8e, 9h8f, 9qt6 – hHPK1 kinase domain (mutant) + inhibitor
6cqd – hHPK1 kinase domain + AMPPNP
8eec – hHPK1 citron homology domain
8v5i – hMAP4K4 kinase domain + inhibitor

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Michal Harel

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