3a15

Structural highlights

Function

OXD_RHOER Catalyzes the dehydration of aldoximes to their corresponding nitrile (PubMed:16233624, PubMed:19740758). Is active toward various arylalkyl- and alkyl-aldoximes, and to a lesser extent toward aryl-aldoximes (PubMed:16233624).^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Kato Y, Yoshida S, Xie SX, Asano Y. Aldoxime dehydratase co-existing with nitrile hydratase and amidase in the iron-type nitrile hydratase-producer Rhodococcus sp. N-771. J Biosci Bioeng. 2004;97(4):250-9. PMID:16233624 doi:10.1016/S1389-1723(04)70200-5
2. ↑ Sawai H, Sugimoto H, Kato Y, Asano Y, Shiro Y, Aono S. X-ray crystal structure of michaelis complex of aldoxime dehydratase. J Biol Chem. 2009 Nov 13;284(46):32089-96. Epub 2009 Sep 8. PMID:19740758 doi:10.1074/jbc.M109.018762