Structural highlights
Function
NSHR_STRAS Specifically methylates the adenosine-1067 in 23S ribosomal RNA. Confers resistance to antibiotic nosiheptide.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Yang H, Wang Z, Shen Y, Wang P, Jia X, Zhao L, Zhou P, Gong R, Li Z, Yang Y, Chen D, Murchie A, Xu Y. Crystal Structure of the Nosiheptide Resistance Methyltransferase of Streptomyces actuosus. Biochemistry. 2010 Jun 15. PMID:20550164 doi:10.1021/bi1005915