Structural highlights
Function
LYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]
Publication Abstract from PubMed
The X-ray crystal structure, NMR binding studies, and enzyme activity of silver(i) metallated hen egg white lysozyme are presented. Primary bonding of silver is observed through His15 with secondary bonding interactions coming from nearby Arg14 and Asp87. A covalently bound nitrate completes a four coordinate binding pocket.
Silver metallation of hen egg white lysozyme: X-ray crystal structure and NMR studies.,Panzner MJ, Bilinovich SM, Youngs WJ, Leeper TC Chem Commun (Camb). 2011 Dec 14;47(46):12479-81. Epub 2011 Oct 31. PMID:22042312[2]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021
- ↑ Panzner MJ, Bilinovich SM, Youngs WJ, Leeper TC. Silver metallation of hen egg white lysozyme: X-ray crystal structure and NMR studies. Chem Commun (Camb). 2011 Dec 14;47(46):12479-81. Epub 2011 Oct 31. PMID:22042312 doi:10.1039/c1cc15908a
