3t35

Structural highlights

Function

DRP1A_ARATH Microtubule-associated force-producing protein that is targeted to the forming cell plate during cytokinesis. Plays also a major role in plasma membrane maintenance and cell wall integrity with implications in vesicular trafficking, polar cell expansion, vascular formation, and other aspects of plant growth and development. Has a GTPase activity.^{[1] [2] [3] [4] [5]}

References

1. ↑ Kang BH, Busse JS, Dickey C, Rancour DM, Bednarek SY. The arabidopsis cell plate-associated dynamin-like protein, ADL1Ap, is required for multiple stages of plant growth and development. Plant Physiol. 2001 May;126(1):47-68. PMID:11351070
2. ↑ Kang BH, Busse JS, Bednarek SY. Members of the Arabidopsis dynamin-like gene family, ADL1, are essential for plant cytokinesis and polarized cell growth. Plant Cell. 2003 Apr;15(4):899-913. PMID:12671086
3. ↑ Hong Z, Geisler-Lee CJ, Zhang Z, Verma DP. Phragmoplastin dynamics: multiple forms, microtubule association and their roles in cell plate formation in plants. Plant Mol Biol. 2003 Oct;53(3):297-312. PMID:14750520
4. ↑ Sawa S, Koizumi K, Naramoto S, Demura T, Ueda T, Nakano A, Fukuda H. DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis. Plant Physiol. 2005 Jun;138(2):819-26. Epub 2005 May 27. PMID:15923323 doi:http://dx.doi.org/pp.105.061689
5. ↑ Yan L, Ma Y, Sun Y, Gao J, Chen X, Liu J, Wang C, Rao Z, Lou Z. Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission. J Mol Cell Biol. 2011 Dec;3(6):378-81. Epub 2011 Nov 22. PMID:22107825 doi:10.1093/jmcb/mjr032