3tbi

Structural highlights

Function

LTACT_BPT4 Activates transcription at late promoters when the sliding clamp is present (PubMed:33602900). Binds to both the host RNA polymerase (RNAP) and the upstream dsDNA (PubMed:33602900, PubMed:8106327).[HAMAP-Rule:MF_04165]^{[1] [2]}

See Also

• RNA polymerase 3D structures

References

1. ↑ Shi J, Wen A, Jin S, Gao B, Huang Y, Feng Y. Transcription activation by a sliding clamp. Nat Commun. 2021 Feb 18;12(1):1131. PMID:33602900 doi:10.1038/s41467-021-21392-0
2. ↑ Winkelman JW, Kassavetis GA, Geiduschek EP. Molecular genetic analysis of a prokaryotic transcriptional coactivator: functional domains of the bacteriophage T4 gene 33 protein. J Bacteriol. 1994 Feb;176(4):1164-71. PMID:8106327 doi:10.1128/jb.176.4.1164-1171.1994