3w5s

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Crystal Structure of Maleylacetate Reductase from Rhizobium sp. strain MTP-10005

Structural highlights

3w5s is a 2 chain structure with sequence from Rhizobium sp. MTP-10005. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.49Å
Ligands:BEN, GOL, SO4
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GRAC_RHIS5 Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:17158677). Catalyzes the reduction of maleylacetate to 3-oxoadipate (PubMed:17158677, PubMed:27040018).[1] [2]

References

  1. Yoshida M, Oikawa T, Obata H, Abe K, Mihara H, Esaki N. Biochemical and genetic analysis of the gamma-resorcylate (2,6-dihydroxybenzoate) catabolic pathway in Rhizobium sp. strain MTP-10005: identification and functional analysis of its gene cluster. J Bacteriol. 2007 Mar;189(5):1573-81. PMID:17158677 doi:10.1128/JB.01675-06
  2. Fujii T, Sato A, Okamoto Y, Yamauchi T, Kato S, Yoshida M, Oikawa T, Hata Y. The crystal structure of maleylacetate reductase from Rhizobium sp. strain MTP-10005 provides insights into the reaction mechanism of enzymes in its original family. Proteins. 2016 Aug;84(8):1029-42. PMID:27040018 doi:10.1002/prot.25046

Contents


PDB ID 3w5s

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