4af8

Structural highlights

Function

MCA2_TRYB2 Cysteine protease that cleaves specifically after arginine or lysine residues.^{[1] [2]}

See Also

• Caspase 3D structures

References

1. ↑ Moss CX, Westrop GD, Juliano L, Coombs GH, Mottram JC. Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing. FEBS Lett. 2007 Dec 11;581(29):5635-9. PMID:18005666 doi:10.1016/j.febslet.2007.11.009
2. ↑ Machado MF, Marcondes MF, Juliano MA, McLuskey K, Mottram JC, Moss CX, Juliano L, Oliveira V. Substrate specificity and the effect of calcium on Trypanosoma brucei metacaspase 2. FEBS J. 2013 Jun;280(11):2608-21. PMID:23506317 doi:10.1111/febs.12248