Structural highlights
Function
TUBZ_BACC1 A tubulin-like, filament forming GTPase; the motor component of the type III plasmid partition system which ensures correct segregation of the pBc10987 plasmid (Probable). Binds GTP and forms filaments (PubMed:22847006). The filaments seed from a DNA centromere-like site (tubC)-TubR complex which extends to surround the TubZ filaments. Highly dynamic filaments grow at the plus end and depolymerize at the minus end, a process called treadmilling. TubR-tubC complexes track the depolymerizing minus end of the filament, probably pulling plasmid within the cell (By similarity).[UniProtKB:Q8KNP3][1] [2]
References
- ↑ Hoshino S, Hayashi I. Filament formation of FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J Biol Chem. 2012 Jul 30. PMID:22847006 doi:10.1074/jbc.M112.373803
- ↑ Hoshino S, Hayashi I. Filament formation of FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J Biol Chem. 2012 Jul 30. PMID:22847006 doi:10.1074/jbc.M112.373803